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Regions

North & South America

Sin Nombre virus in the US Four Corners. Andes virus across Patagonia (Argentina/Chile). HPS endemic at low levels; Andes is the only hantavirus with documented person-to-person transmission.

Last updated: 2026-05-08

Endemic strains in this region

  • Sin Nombre virus — US Four Corners (deer mouse reservoir, Peromyscus maniculatus)
  • Andes virus — Patagonian corridor (Argentina, Chile); rare person-to-person transmission documented
  • Araraquara virus — Brazilian cerrado (Necromys lasiurus reservoir)
  • Choclo virus — Panama; lower fatality strain

Reporting & case patterns

HPS in the Americas runs a few hundred cases per year, dominated by Argentina, Chile, USA (Four Corners) and Brazil. Case fatality is high — CDC reports ~38% in the US. Andes virus outbreaks in Patagonia produce most international media attention.

Regional prevention notes

Same baseline as elsewhere: seal entry points, ventilate before cleaning, wet droppings before removal, never sweep or vacuum. In endemic Andes regions, occupational risk for park rangers, foresters and seasonal cabin cleaners is highest.

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